Protein-structure-sensitive mid-infrared optoacoustic microscopy enables label-free assessment of drug therapy in myeloma cells
F. Gasparin, M. R. Tietje, E. Katab, A. Nurdinova, T. Yuan, A. Chmyrov, N. Uluc, D. Jüstel, F. Bassermann, V. Ntziachristos, M. A. Pleitez
This paper introduces a mid-infrared optoacoustic microscopy technique to label-free monitor drug therapy effects on myeloma cells by detecting intermolecular β-sheet formation.
bioRxiv · Feb 21, 2024 · PreprintBiophysics