M. Azkargorta

ANKRD55 interacts with an IFT-B-like complex in microglia

The paper identifies ANKRD55 interacting with an IFT-B-like complex in microglia, suggesting a role in ciliary transport independent of ciliogenesis.

Trajectory analysis of hepatic stellate cell differentiation reveals metabolic regulation of cell commitment and fibrosis

This study maps the differentiation trajectory of iPSCs to hepatic stellate cells, identifying RORA as a key regulator of metabolic reprogramming and fibrosis.

Thermodynamic Stabilization of Human Frataxin

This study thermodynamically stabilizes human frataxin using computational methods, improving its stability and resistance to proteolysis without compromising function.

BioE3 enables the identification of bona fide targets of E3 ligases

BioE3 identifies substrates of UbL E3 ligases by site-specific biotinylation and proteomic analysis, revealing both known and novel targets for various E3 ligases.

Phenotypic and omics analyses of the Sordariomycetes Marquandomyces marquandii and Albophoma yamanashiensis isolated from estuarine sediments.

The paper isolates and characterizes two marine filamentous fungi, analyzing their secondary metabolite production and enzymatic responses to algal polysaccharides.

NF-κB c-REL-OTUD4 axis regulates B-cell receptor in B-cell lymphoma

The paper identifies the c-REL-OTUD4 axis as a regulator of BCR in B-cell lymphoma, showing OTUD4 stabilizes c-REL and BCR, and its downregulation inhibits lymphoma cell growth.

Identification of proximal SUMO-dependent interactors using SUMO-ID

This study introduces SUMO-ID, a method to identify SUMO-dependent protein interactors using TurboID and protein-fragment complementation, revealing novel interactions related to transcription, DNA damage, and stress response.