A. K. Sahoo

An integrative data-centric approach to derivation and characterization of an adverse outcome pathway network for cadmium-induced toxicity

This study constructs the first adverse outcome pathway network for inorganic cadmium toxicity by integrating data from multiple sources and analyzing key events and relationships.

First complete genome characterization of an Indian pigeon pox virus directly from a clinical sample

The paper reports the first complete genome of an Indian pigeon pox virus and performs comparative genomics analysis to understand its genetic features and phylogenetic relationships.

Cheminformatics analysis of multi-target structure-activity landscape of environmental chemicals binding to human endocrine receptors

This study analyzes the structure-activity landscape of environmental chemicals binding to multiple human endocrine receptors to improve toxicity prediction models.

Analysis of structure-activity and structure-mechanism relationships among thyroid stimulating hormone receptor binding chemicals by leveraging ToxCast library

The paper analyzes structure-activity and structure-mechanism relationships of TSHR-binding chemicals using ToxCast data to improve predictive toxicity models.

Identification of activity cliffs in structure-activity landscape of androgen receptor binding chemicals

The paper identifies activity cliffs in the structure-activity landscape of androgen receptor binding chemicals, revealing heterogeneity and improving predictive toxicity models.

Scaffold and structural diversity of the secondary metabolite space of medicinal fungi

This study analyzes the scaffold and structural diversity of secondary metabolites from medicinal fungi and compares them to approved drugs and other libraries, finding high diversity and minimal overlap with existing drugs.

IMPPAT 2.0: an enhanced and expanded phytochemical atlas of Indian medicinal plants

IMPPAT 2.0 is a comprehensive phytochemical atlas of Indian medicinal plants, providing curated data on 4010 plants, 17967 phytochemicals, and traditional formulations.

Concerted interactions between multiple gp41 trimers and the target cell lipidome may be required for HIV-1 entry

This study uses molecular dynamics simulations to show that multiple gp41 trimers and host cell lipidomes are required for efficient HIV-1 membrane fusion.