Carbon Dioxide Controls Fungal Fitness and Skin Tropism of Candida auris
P.-C. Trinh, P. Penninger, S. Seiser, N. Khunweeraphong, D. Moser, T. Bitencourt, H. Arzani, W. Chen, L.-M. Zenz, A. Knarr, D. Cerbu, S. Jenull, C. Muller, M. Lackner, G. Ianiri, , K. Kuchler
This study identifies a carbonic sensing pathway (CSP) in Candida auris that enhances drug resistance and skin colonization through mechanisms involving ROS response, cell wall remodeling, and energy metabolism.
bioRxiv · Apr 12, 2024 · PreprintMicrobiology