C. Muller

Carbon Dioxide Controls Fungal Fitness and Skin Tropism of Candida auris

This study identifies a carbonic sensing pathway (CSP) in Candida auris that enhances drug resistance and skin colonization through mechanisms involving ROS response, cell wall remodeling, and energy metabolism.

Metabolic fingerprinting reveals roles of Arabidopsis thaliana BGLU1, BGLU3 and BGLU4 in glycosylation of various flavonoids

This study identifies the roles of BGLU1, BGLU3, and BGLU4 in glycosylating already glycosylated flavonoids in Arabidopsis thaliana using reverse genetics and metabolic fingerprinting.

Chemodiversity affects preference for Tanacetum vulgare chemotypes in two aphid species

The paper tests how chemodiversity in Tanacetum vulgare affects aphid preference, finding that chemotype composition and diversity influence attractiveness differently in two aphid species.

Extra-cellular matrix remodeling as a unique mechanism of expansion of periprostatic adipose tissue: a potential driver of prostate cancer aggressiveness

The paper defines abundant periprostatic adipose tissue using a statistical approach and shows it is associated with prostate cancer aggressiveness through extracellular matrix remodeling.

Hepatic mTORC2 compensates for loss of adipose mTORC2 in mediating energy storage and glucose homeostasis

This study shows that loss of adipose mTORC2 leads to increased hepatic lipogenesis and hypertriglyceridemia, but simultaneous inhibition in both tissues causes severe insulin resistance.

The Image Data Explorer: interactive exploration of image-derived data

The paper introduces the Image Data Explorer, a web tool for interactive exploration of image-derived data in bioimage analysis.

Human land-use impacts viral diversity and abundance in a New Zealand river

This study examines how human land-use affects viral diversity and abundance in a New Zealand river, finding higher diversity in urban sites and novel viruses linked to agriculture and human impact.

Discovery of small molecule inhibitors of the PTK7/β-catenin interaction targeting the Wnt signaling pathway in colorectal cancer

This study identifies small molecule inhibitors of the PTK7/β-catenin interaction in colorectal cancer, showing anti-proliferative effects in cells with Wnt pathway mutations.

The latitudinal diversity gradient in brush-footed butterflies (Nymphalidae): conserved ancestral tropical niche but different continental histories.

This study evaluates hypotheses for the latitudinal diversity gradient in Nymphalidae butterflies, finding that low extinction rates and historical dispersal patterns, rather than speciation rates, explain diversity patterns.

Injection molded open microfluidic well plate inserts for user-friendly coculture and microscopy

The paper introduces injection molded open microfluidic devices for coculture and microscopy, enabling study of cell interactions in standard cell culture workflows.

Adipocyte vesicles: ‘all-in-one’ packages that stimulate tumor mitochondrial metabolism and dynamics

This study shows adipocyte extracellular vesicles enhance melanoma fatty acid oxidation and migration via lipid droplet-stored fatty acids, with obesity amplifying this effect through increased fatty acid transport.

Yellow adipocytes comprise a new adipocyte sub-type present in human bone marrow

The paper identifies a distinct adipocyte sub-type in human bone marrow, termed yellow adipocytes, characterized by unique lipid metabolism and absence of lipolytic responses.