Protein homeostasis is maintained by proteasomes containing PSMB9 induced by EEF1A2 upon mitochondrial stress
M. Kim, L. Samluk, T. M. Stepkowski, I. Suppanz, R. A. Serwa, A. Kodron, B. Warscheid, A. Chacinska
The paper shows that mitochondrial stress increases proteasome activity via HSPB1 and PSMB9, which are regulated by EEF1A2 and localized near mitochondria to prevent protein aggregation.
bioRxiv · Dec 23, 2021 · PreprintCell Biology