13C ENDOR Spectroscopy-Guided MD Computations Reveals the Structure of the Enzyme-Substrate Complex of an Active, N-linked Glycosylated Lipoxygenase
A. Sharma, C. Whittington, M. Jabed, S. G. Hill, A. Kostenko, T. Yu, P. Li, B. M. Hoffman, A. R. Offenbacher
This paper uses 13C/1H ENDOR spectroscopy-guided MD simulations to determine the structure of an active fungal lipoxygenase-substrate complex, revealing evolutionary insights into enzyme function.
bioRxiv · Dec 7, 2022 · PreprintBiochemistry