Author

B. M. Hoffman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:fungi (other)· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Kostenko· 1 shared A. R. Offenbacher· 1 shared A. Sharma· 1 shared C. D. James· 1 shared C. Whittington· 1 shared M. Jabed· 1 shared P. Li· 1 shared S. G. Hill· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

A. Kostenko

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2 papers

Recent·Most cited

13C ENDOR Spectroscopy-Guided MD Computations Reveals the Structure of the Enzyme-Substrate Complex of an Active, N-linked Glycosylated Lipoxygenase

A. Sharma, C. Whittington, M. Jabed, S. G. Hill, A. Kostenko, T. Yu, P. Li, B. M. Hoffman, A. R. Offenbacher

This paper uses 13C/1H ENDOR spectroscopy-guided MD simulations to determine the structure of an active fungal lipoxygenase-substrate complex, revealing evolutionary insights into enzyme function.

bioRxiv · Dec 7, 2022 · PreprintBiochemistry

13C Electron Nuclear Double Resonance Spectroscopy Shows Acetyl-CoA Synthase Binds Two Substrate CO in Multiple Binding Modes and Reveals the Importance of a CO-Binding 'Alcove'

C. D. James, S. Wiley, S. W. Ragsdale, B. M. Hoffman

This paper uses 13C-ENDOR spectroscopy to show Acetyl-CoA Synthase binds two CO molecules in different modes, highlighting the role of an alcove in stabilizing the Ni(I)-CO intermediate.

bioRxiv · Jun 23, 2020Biochemistry