A high-fidelity in vitro model of the human intestinal epithelium
S. Fujii, S. T. Espenschied, V. Anand, J. Bettencourt-Silva, Y. Han, G. Ito, A. Koseki, A. Kosugi, J. Kozlowski, R. Matsumoto, S. Meng, N. Mulligan, R. J. Musich, K. Newhall, E. Ohshina, , T. S. Stappenbeck
This paper develops an in vitro model of the human intestinal epithelium that closely mimics in vivo cell types using single-cell transcriptomics and a biomedical foundation model.
bioRxiv · Jan 1, 2024 · PreprintCell Biology