ImmunologybioRxiv
Intestinal Serum Amyloid A suppresses systemic neutrophil activation and bactericidal activity in response to microbiota colonization
C. C. Murdoch, S. T. Espenschied, M. A. Matty…·J. F. Rawls
This study identifies Serum Amyloid A (Saa) as a mediator of intestinal microbiota regulation of neutrophil function, showing it suppresses inflammation and bacterial killing while enhancing wound migration.
DOI 10.1371/journal.ppat.1007381