Structures of the heart specific SERCA2a Ca2+-ATPase
P. Nissen, J. De Raeymaecker, A. Kotsubei, N. D. Drachmann, R. Derua, S. Smaardijk, J. L. Andersen, I. Vandecaetsbeek, J. Chen, M. De Mayer, E. Waelkens, C. E. Olesen, P. Vangheluwe
The paper presents the first crystal structures of SERCA2a, revealing structural and regulatory differences from SERCA1a and providing insights into its function in cardiac muscle.
bioRxiv · Jun 12, 2018Biochemistry