The Physiological Landscape and Specificity of Antibody Repertoires
L. Csepregi, K. B. Hoehn, D. Neumeier, J. M. Taft, S. Friedensohn, C. R. Weber, A. Kummer, F. Sesterhenn, B. E. Correia, S. T. Reddy
This study analyzes antibody repertoires across multiple lymphoid organs in immunized mice, finding that strong humoral responses lead to consolidated, overlapping B-cell clones and a uniform but redundant physiological landscape.
bioRxiv · Sep 15, 2021 · PreprintImmunology