Bile acids accumulate norovirus-like particles and enhance binding to and entry into human enteric epithelial cells
E. Palm, K. Danskog, S. Nord, M. Becker, H. Tanner, L. Sandblad, D. Öhlund, A. Lenman, N. Arnberg
This study shows that hydrophobic bile acids enhance norovirus VLP attachment and entry into human duodenal cells by aggregating virions near the cell surface.
bioRxiv · Apr 28, 2023 · PreprintMicrobiology