Developing Cyclic Peptomers as Broad-Spectrum Gram negative Bacterial Type III Secretion System Inhibitors
H. Lam, T. Lau, A. Lentz, J. Sherry, A. Cabrera-Cortez, K. Hug, J. Engel, S. Lokey, V. Auerbach Stone
This paper identifies a cyclic peptomer, 4EpDN, that broadly inhibits Gram-negative bacterial type III secretion systems without affecting bacterial growth or other secretory systems.
bioRxiv · Aug 3, 2020Microbiology