Author

H. Lam

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Animal Behavior & Cognition· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:behavioral assay· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. B. Lawrence· 1 shared A. Cabrera-Cortez· 1 shared A. J. Hickey· 1 shared A. Lentz· 1 shared A. MacNeil· 1 shared A. Rosenthal· 1 shared A. Walz· 1 shared B. L. Nielsen· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperAnimal Behavior & Cognition

A. B. Lawrence

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Modified BPaL Regimen for Tuberculosis Treatment replaces Linezolid with Inhaled Spectinamides

M. Zohaib Ali, T. S. Dutt, A. MacNeil, A. Walz, J. Patterson, C. Pearce, H. Lam, J. S. Philp, R. Lee, J. Liu, G. T. Robertson, A. J. Hickey, B. Meibohm, M. Gonzalez-Juarrero

This paper evaluates a modified BPaL regimen replacing linezolid with inhaled spectinamide 1599 for tuberculosis treatment, showing similar efficacy while avoiding linezolid-associated adverse events.

bioRxiv · Nov 16, 2023Microbiology

The multi-Siglec inhibitor AL009 reprograms suppressive macrophages and activates innate and adaptive tumor immunity

S. C. Nalle, H. Lam, L. Leung, S. Liang, D. Maslyar, A. Rosenthal

AL009, a multi-Siglec inhibitor, reprograms suppressive macrophages and enhances anti-tumor immunity in preclinical models.

bioRxiv · Aug 2, 2023 · PreprintCancer Biology

Developing Cyclic Peptomers as Broad-Spectrum Gram negative Bacterial Type III Secretion System Inhibitors

H. Lam, T. Lau, A. Lentz, J. Sherry, A. Cabrera-Cortez, K. Hug, J. Engel, S. Lokey, V. Auerbach Stone

This paper identifies a cyclic peptomer, 4EpDN, that broadly inhibits Gram-negative bacterial type III secretion systems without affecting bacterial growth or other secretory systems.

Antimicrobial Agents and Chemotherapy · Jun 17, 2021Peer-reviewedMicrobiology

Odour conditioning of positive affective states: Rats can learn to associate an odour with being tickled

V. Bombail, N. Jerome, H. Lam, S. Muszlak, S. Meddle, A. B. Lawrence, B. L. Nielsen

This study shows that rats can learn to associate an odour with the positive experience of being tickled, as evidenced by increased ultrasonic vocalizations.

bioRxiv · Feb 14, 2019Animal Behavior & Cognition