The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver
N. Hruschka, M. Subijana, O. Grana-Castro, F. Del Cano-Ochoa, L. Pare Brunet, A. Sagrera, A. De Reynies, D. Andreu, J. Sutton, I. Chernukhin, S.-F. Chin, C. Caldas, A. Lluch, O. Burgues, B. Bermejo, , P. Martinelli
The paper investigates the context-dependent oncogenic effects of the GATA3 X308_Splice mutation in breast cancer, showing its differential impact based on hormonal status.
bioRxiv · Jun 8, 2019Cancer Biology