Author

A. Prat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2

Frequent Co-Authors

A. De Reynies· 1 shared A. Finzi· 1 shared A. Llombart-Cussac· 1 shared A. Lluch· 1 shared A. Nicolas· 1 shared A. S. Flores· 1 shared A. Sagrera· 1 shared A. Tauzin· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. De Reynies

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Disease-associated astrocyte epigenetic memory promotes CNS pathology

H.-G. Lee, J. M. Rone, Z. Li, C. Faust Akl, S. W. Shin, J.-H. Lee, L. E. Flausino, F. Pernin, C.-C. Chao, K. L. Kleemann, L. Srun, T. Illouz, F. Giovannoni, M. Charabati, L. M. Sanmarco, , F. J. Quintana

This study identifies an epigenetically controlled memory astrocyte subset that exacerbates CNS pathology in EAE and MS by promoting pro-inflammatory responses.

bioRxiv · Jan 4, 2024Immunology

In situ single-cell analysis of canonical breast cancer biomarkers: phenotypic heterogeneity and implications on response to HER2 targeting agents.

G. Serna, E. Garcia, R. Fasani, X. Guardia, T. Pascual, L. Pare, F. Ruiz-Pace, A. Llombart-Cussac, J. Cortes, A. Prat, P. G. Nuciforo

The paper analyzes HER2-positive breast cancer tumors at the single-cell level to identify phenotypic heterogeneity and its implications for response to HER2-targeted therapies.

bioRxiv · Sep 21, 2022 · PreprintPathology

A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile

G. Sannier, A. Nicolas, M. Dube, L. Marchitto, M. Nayrac, O. Tastet, A. Tauzin, R. Lima-Barbosa, M. Laporte, R. Cloutier, A. S. Flores, M. Boutin, S. Y. Gong, M. Benlarbi, S. Ding, , D. E. Kaufmann

bioRxiv · Sep 5, 2022Immunology

The GATA3 X308_Splice breast cancer mutation is a hormone context-dependent oncogenic driver

N. Hruschka, M. Subijana, O. Grana-Castro, F. Del Cano-Ochoa, L. Pare Brunet, A. Sagrera, A. De Reynies, D. Andreu, J. Sutton, I. Chernukhin, S.-F. Chin, C. Caldas, A. Lluch, O. Burgues, B. Bermejo, , P. Martinelli

The paper investigates the context-dependent oncogenic effects of the GATA3 X308_Splice mutation in breast cancer, showing its differential impact based on hormonal status.

bioRxiv · Jun 8, 2019Cancer Biology

Multiplexed imaging of immune cells in staged multiple sclerosis lesions by mass cytometry

V. Ramaglia, S. S. Mohamed, K. Legg, O. Rojas, S. Zandee, F. Fu, O. Ornatsky, E. C. Swanson, A. Prat, T. McKee, J. Gommerman

This study uses imaging mass cytometry to analyze immune cell phenotypes and interactions in multiple sclerosis lesions across different stages.

bioRxiv · May 18, 2019Immunology