Author

A. Loas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

B. L. Pentelute· 3 shared A. R. Loftis· 2 shared C. K. Schissel· 2 shared G. Zhang· 2 shared A. B. Malmberg· 1 shared A. J. Quartararo· 1 shared C. Backlund· 1 shared C. E. Farquhar· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioengineering

B. L. Pentelute

Mutual co-authors in cluster

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3 papers

Recent·Most cited

In-cell penetration selection-mass spectrometry produces noncanonical peptides for antisense delivery

C. K. Schissel, C. E. Farquhar, A. Loas, A. B. Malmberg, B. L. Pentelute

This paper develops in-cell PS-MS to discover synthetic peptides for delivering macromolecules to the cytosol, identifying Pep1a as a highly effective peptide for antisense delivery.

bioRxiv · Apr 13, 2022Bioengineering

Erythrocyte-targeted immunomodulatory antigens enabled by in vivo selection of D-peptides

A. R. Loftis, G. Zhang, C. Backlund, A. J. Quartararo, N. Pishesha, C. K. Schissel, D. Garafola, A. Loas, R. J. Collier, H. Ploegh, D. J. Irvine, B. L. Pentelute

The paper identifies a D-peptide that targets murine erythrocytes and reduces anti-drug antibody responses when conjugated to therapeutic proteins.

bioRxiv · Jul 15, 2020 · PreprintBioengineering

Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD

G. Zhang, S. Pomplun, A. R. Loftis, X. Tan, A. Loas, B. L. Pentelute

This study investigates ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD using molecular dynamics simulations and peptide synthesis, finding that a 23-mer peptide fragment binds with micromolar affinity to insect-derived RBD but not HEK-expressed RBD.

bioRxiv · Mar 19, 2020 · PreprintBioengineering