Author

A. M. Lambowitz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. Yao· 2 shared R. M. Nottingham· 2 shared A. M. Lentzsch· 1 shared A. Roy· 1 shared G. Deschamps-Francoeur· 1 shared J. L. Stamos· 1 shared L. Faucher-Giguere· 1 shared M. J. Shurtleff· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

J. Yao

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

High-grade Ovarian Cancer Associated H/ACA snoRNAs Promote Cancer Cell Proliferation and Survival

L. Faucher-Giguere, A. Roy, G. Deschamps-Francoeur, S. Couture, R. M. Nottingham, A. M. Lambowitz, M. S. Scott, S. Abou Elela

This study identifies H/ACA snoRNAs in high-grade ovarian cancer that promote cell proliferation and survival by inhibiting apoptosis and enhancing invasion.

bioRxiv · Aug 24, 2021Cancer Biology

Structural basis for template switching by a group II intron-encoded non-LTR-retroelement reverse transcriptase

A. M. Lentzsch, J. L. Stamos, J. Yao, R. Russell, A. M. Lambowitz

This study determines the structure of a group II intron RT template-switching complex, revealing mechanisms of template switching and non-templated addition, and their implications for RNA-seq and retroelement function.

bioRxiv · May 13, 2021Biochemistry

Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes

M. M. Temoche-Diaz, M. J. Shurtleff, R. M. Nottingham, J. Yao, R. P. Fadadu, A. M. Lambowitz, R. Schekman

The paper identifies distinct miRNA sorting mechanisms in cancer cell-derived extracellular vesicles, showing selective and non-selective pathways mediated by Lupus La and miR-122 motifs.

bioRxiv · Apr 17, 2019Biochemistry