Author

M. J. Shurtleff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

J. S. Weissman· 2 shared J. Yao· 2 shared K. D. Popova· 2 shared R. M. Nottingham· 2 shared R. Schekman· 2 shared A. Frost· 1 shared A. Lambowitz· 1 shared A. M. Lambowitz· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

J. S. Weissman

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Author profile →

4 papers

Recent·Most cited

Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients

L. E. Miller-Vedam, B. Bräuning, K. D. Popova, N. T. Schirle Oakdale, J. L. Bonnar, J. R. Prabu, E. A. Boydston, N. Sevillano, M. J. Shurtleff, R. M. Stroud, C. S. Craik, B. Schulman, A. Frost, J. S. Weissman

The paper reveals the structural and mechanistic basis of EMC's role in biogenesis of distinct transmembrane proteins through cryo-EM structures and functional studies.

bioRxiv · Sep 2, 2020Biophysics

The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins

A. M. Ngo, M. J. Shurtleff, K. D. Popova, J. Kulsuptrakul, J. S. Weissman, A. S. Puschnik

This study shows the ER membrane protein complex is essential for correct topology and stable expression of flavivirus polyproteins by preventing degradation of NS4A-NS4B.

bioRxiv · Sep 4, 2019Microbiology

Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes

M. M. Temoche-Diaz, M. J. Shurtleff, R. M. Nottingham, J. Yao, R. P. Fadadu, A. M. Lambowitz, R. Schekman

The paper identifies distinct miRNA sorting mechanisms in cancer cell-derived extracellular vesicles, showing selective and non-selective pathways mediated by Lupus La and miR-122 motifs.

bioRxiv · Apr 17, 2019Biochemistry

A broad role for YBX1 in defining the small non-coding RNA composition of exosomes

M. J. Shurtleff, J. Yao, Y. Qin, R. M. Nottingham, M. Temoche-Diaz, R. Schekman, A. Lambowitz

The paper uses TGIRT-seq to analyze RNA in exosomes, revealing that YBX1 influences the sorting of small non-coding RNAs like tRNAs and Y RNAs into exosomes.

bioRxiv · Jul 11, 2017Cell Biology