A Pan-respiratory Antiviral Chemotype Targeting a Host Multiprotein Complex
M. Michon, A. Mueller-Schiffmann, A. F. Lingappa, S. F. Yu, L. Du, F. Deiter, S. Mallesh, J. Crabtree, U. F. Lingappa, A. Macieik, L. Mueller, P. N. Ostermann, M. Andree, O. Adams, H. Schaal, , K
The paper identifies a novel antiviral chemotype effective against multiple respiratory viruses by targeting a host multi-protein complex involved in viral lifecycle and innate immunity.
bioRxiv · Jan 17, 2021Biochemistry