Author

A. Mackenzie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Bernardi· 1 shared A. V. Nunn· 1 shared C. H. Wong· 1 shared C. Oswald· 1 shared E. L. Thomas· 1 shared E. Mercier· 1 shared I. Kalampouka· 1 shared J. D. Bell· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiochemistry

A. Bernardi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Urban wastewater contains a functional human antibody repertoire of mucosal origin

S. Stephenson, W. Eid, C. H. Wong, E. Mercier, P. M. D'Aoust, M. P. Kabir, S. Baral, K. A. Gilbride, C. Oswald, S. E. Straus, A. Mackenzie, R. Delatolla, T. E. Graber

The paper identifies and characterizes a human antibody repertoire from wastewater, showing it can track immune correlates and aid in vaccine efficacy assessment.

bioRxiv · Jun 2, 2024Immunology

Near infrared-light treatment alters mitochondrial homeostasis to induce senescence in breast cancer cells

I. Kalampouka, R. R. Mould, S. W. Botchway, A. Mackenzie, A. V. Nunn, E. L. Thomas, J. D. Bell

This study shows that near infrared-light treatment increases senescence in breast cancer cells by altering mitochondrial homeostasis, without affecting non-cancerous cells.

bioRxiv · Jul 6, 2023Cell Biology

Meiotic Cells Escape Prolonged Spindle Checkpoint Activity Through Premature Silencing and Slippage

A. MacKenzie, V. Vicory, S. Lacefield

This study compares spindle checkpoint responses in mitotic and meiotic budding yeast cells, finding that meiotic cells escape checkpoint arrest more quickly through silencing and slippage mechanisms.

bioRxiv · Jan 2, 2023 · PreprintCell Biology

Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics

J. E. Heggelund, A. Mackenzie, T. Martinsen, P. Cheshev, A. Bernardi, U. Krengel

This paper presents crystal structures of bacterial enterotoxins complexed with GM1 mimics, revealing molecular interactions that could guide the design of new cholera prophylactics.

Scientific Reports · May 24, 2017Peer-reviewedBiochemistry