Author

C. H. Wong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

K.-F. To· 3 shared Y. Chen· 3 shared C. H. Li· 2 shared J. H.-M. Tong· 2 shared Q. He· 2 shared S. L. Chan· 2 shared C. Kuhlberg· 1 shared C. Qian· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersCancer Biology

K.-F. To

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 1, 2023

Genome-scale requirements for dynein-based trafficking revealed by a high-content arrayed CRISPR screen

C. H. Wong, S. Wingett, C. Qian…·S. L. Bullock

The paper uses a CRISPR screen to identify genes critical for dynein-based trafficking, revealing novel regulators and functional relationships in microtubule transport.

DOI 10.1101/2023.03.01.530592

humangenetic perturbation / CRISPR

𝕏 PostBluesky

MicrobiologybioRxivPreprintFeb 6, 2021

Subgenomic RNAs as molecular indicators of asymptomatic SARS-CoV-2 infection

C. H. Wong, C. Y. Ngan, R. L. Goldfeder…·C.-L. Wei

The paper examines subgenomic RNA (sgRNA) expression and structural variations in symptomatic and asymptomatic SARS-CoV-2 infections to correlate with disease severity.

DOI 10.1101/2021.02.06.430041

humanlong-read sequencing

𝕏 PostBluesky

Cancer BiologybioRxivOct 21, 2019

Ectopic HOTTIP Expression Induces Non-canonical Transactivation Pathways to Promote Growth and Invasiveness in Pancreatic Ductal Adenocarcinoma

C. H. Wong, C. H. Li, Q. He…·Y. Chen

This study identifies HOTTIP's role in promoting pancreatic ductal adenocarcinoma through both canonical HOXA13-mediated and non-canonical WDR5-MLL1-H3K4me3 pathways.

DOI 10.1016/j.canlet.2020.02.038

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivOct 21, 2019

The Establishment of CDK9/ RNA PolII/H3K4me3/DNA Methylation Feedback Promotes HOTAIR Expression by RNA Elongation Enhancement in Cancer

C. H. Wong, C. H. Li, Q. He…·Y. Chen

The paper identifies a positive feedback loop involving CDK9, histone modification, and DNA methylation that enhances HOTAIR expression through transcription elongation in cancer.

DOI 10.1016/j.ymthe.2022.01.038

humanDNA methylation

𝕏 PostBluesky

Cancer BiologybioRxivOct 3, 2019

CircFOXK2 Promotes Tumor Growth and Metastasis of Pancreatic Ductal Adenocarcinoma via Complexing with RNA Binding Proteins and Sponging MiR-942

C. H. Wong, U. K. Lou, Y. Li…·Y. Chen

This study identifies circFOXK2 as an oncogenic circRNA in PDAC that promotes tumor growth and metastasis by acting as a miR-942 sponge and interacting with RNA-binding proteins.

DOI 10.1016/j.pan.2020.07.369

humanbulk RNA-seq

𝕏 PostBluesky