Author

A. Bernardi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 2 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

C. Vives· 2 shared F. Fieschi· 2 shared M. Thepaut· 2 shared A. Mackenzie· 1 shared B. S. Harris· 1 shared C. Pifferi· 1 shared D. Fenel· 1 shared F. Lasala· 1 shared

Activity by Year

2017-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

C. Vives

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist

M. Thepaut, J. Luczkowiak, C. Vives, N. Labiod, I. Bally, F. Lasala, Y. Grimoire, D. Fenel, S. Sattin, N. Thielens, G. Schoehn, A. Bernardi, R. Delgado, F. Fieschi

The paper shows DC/L-SIGN receptors on antigen-presenting cells enhance SARS-CoV-2 trans-infection, which can be blocked by a glycomimetic compound.

bioRxiv · Aug 9, 2020Immunology

Development and simulation of fully glycosylated molecular models of ACE2-Fc fusion proteins and their interaction with the SARS-CoV-2 spike protein binding domain

A. Bernardi, Y. Huang, B. S. Harris, Y. Xiong, S. Nandi, K. A. McDonald, R. Faller

The paper develops and simulates fully glycosylated ACE2-Fc fusion proteins and their interaction with SARS-CoV-2 spike protein RBD, showing glycan effects on conformation and optimizing glycosylation modeling algorithms.

PLOS ONE · Aug 5, 2020Peer-reviewedBiophysics

Development Of C-Type Lectin Oriented Surfaces For High Avidity Glycoconjugates: Towards Mimicking Multivalent Interactions On The Cell Surface

V. Porkolab, C. Pifferi, I. Sutkeviciute, S. Ordanini, M. Taouai, M. Thepaut, C. Vives, M. Benazza, A. Bernardi, O. Renaudet, F. Fieschi

This paper develops SPR direct interaction assays for DC-SIGN to better assess multivalent glycocluster binding, showing that scaffold architecture, valency, and glycomimetic ligands are critical for achieving nanomolar affinities.

Organic & Biomolecular Chemistry · Jan 1, 2020Peer-reviewedBiochemistry

Towards new cholera prophylactics and treatment: Crystal structures of bacterial enterotoxins in complex with GM1 mimics

J. E. Heggelund, A. Mackenzie, T. Martinsen, P. Cheshev, A. Bernardi, U. Krengel

This paper presents crystal structures of bacterial enterotoxins complexed with GM1 mimics, revealing molecular interactions that could guide the design of new cholera prophylactics.

Scientific Reports · May 24, 2017Peer-reviewedBiochemistry