A. Marco

The p90 Ribosomal S6 Kinases 2 and 4 promote Prostate Cancer cell proliferation in androgen-dependent and independent ways

This study shows RSK2 and RSK4 promote prostate cancer proliferation through distinct mechanisms, both dependent and independent of androgen signaling.

The chromosomal distribution of sex-biased microRNAs in Drosophila is non-adaptive

The paper examines sex-biased microRNA distribution in Drosophila, finding that male-biased microRNAs are enriched on the X chromosome, contradicting demasculinization theories.

A diabetic milieu increases cellular susceptibility to SARS-CoV-2 infections in engineered human kidney organoids and diabetic patients

This study shows that a diabetic environment increases SARS-CoV-2 susceptibility in kidney organoids and patients by upregulating ACE2, which is critical for viral replication.

Pervasive selection against microRNA target sites in human populations

The paper shows that new microRNA target sites are selected against in human populations, with higher population differentiation observed for lost target sites than for newly gained ones.

No evidence of functional co-adaptation between clustered microRNAs

The paper reanalyzes claims of functional co-adaptation between clustered microRNAs and finds no evidence of such co-adaptation after correcting for sequence and target overlap biases.

Influence of fats, carotenoids and POPs on the reproduction of the leatherback turtle

This study examines fatty acids, carotenoids, and POPs in leatherback turtle eggs, finding positive correlations between carotenoids and egg viability, and between POPs and PUFAs, suggesting potential masking of contaminant effects on reproduction.

The impact of population variation in the analysis of microRNA target sites

The paper examines how population variation affects microRNA target site detection and finds that African populations have many undetected target sites due to reference genome limitations.