F. Gonzalez

Reduced Telomerase Interaction with Telomeres Alters Meiotic Chromosome Motion and Gamete Viability

This study shows that reduced telomerase interaction with telomeres in yeast affects meiotic chromosome motion and gamete viability by altering recombination and cytoskeletal forces.

Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes

This study shows that Fam49b suppresses TCR signaling to prevent excessive negative selection in thymocytes, ensuring normal T cell development.

A diabetic milieu increases cellular susceptibility to SARS-CoV-2 infections in engineered human kidney organoids and diabetic patients

This study shows that a diabetic environment increases SARS-CoV-2 susceptibility in kidney organoids and patients by upregulating ACE2, which is critical for viral replication.

An intranasal ASO therapeutic targeting SARS-CoV-2

This paper develops an intranasal ASO therapy targeting SARS-CoV-2 RNA that effectively prevents viral replication in multiple models and variants.

Formation of Phage Lysis Patterns and Implications on Co-Propagation of Phages and Motile Host Bacteria

The paper investigates phage-bacteria coexistence and co-propagation by combining experiments and modeling, revealing a sector-shaped lysis pattern indicative of co-propagation and showing it depends on intrinsic properties, not external factors.

Using virtual reality and thermal imagery to improve statistical modelling of vulnerable and protected species

The paper combines virtual reality and thermal imagery with statistical models to improve koala distribution predictions and conservation efforts.

PIKfyve deficiency in myeloid cells impairs lysosomal homeostasis in macrophages and promotes systemic inflammation in mice

This study shows that PIKfyve deficiency in myeloid cells impairs lysosomal function, leading to systemic inflammation and tissue infiltration in mice.

The Drosophila pheromone Z4-11Al is encoded together with habitat olfactory cues and mediates species-specific communication