A system for functional studies of the major virulence factor of malaria parasites
J. Cronshagen, J. Allweier, J. P. Mesen-Ramirez, J. Staecker, A. V. Vaaben, G. Ramon-Zamorano, I. Naranjo, M. Graser, P. Lopez-Barona, S. Ofori, P. W. Jansen, J. Hornebeck, F. Kieferle, A. Murk, E. Martin, , T. Spielmann
The paper develops a system to study PfEMP1, a key malaria parasite virulence factor, by generating parasites expressing a single PfEMP1 variant and enabling genome edits to investigate its function.
bioRxiv · Apr 30, 2024Microbiology