An unusual trafficking domain in MSRP6 defines a complex needed for Maurer's clefts anchoring and maintenance in P. falciparum infected red blood cells
A. Blancke Soares, J. Staecker, S. Schwald, W. A. M. Hoijmakers, N. G. Metwally, J. Cronshagen, H. Schoeler, S. Flemming, K. Hoehn, U. Froehlke, P. Mesen-Ramirez, B. Bergmann, M. Khosh-Naucke, I. Bruchhaus, R. Bartfai, T. Spielmann
The paper identifies a novel domain in MSRP6 that mediates Maurer's clefts anchoring and maintenance in P. falciparum, but shows these functions are dispensable for PfEMP1 transport and cytoadherence.
bioRxiv · Dec 3, 2021 · PreprintMicrobiology