S. Ofori

Chemoproteomics identifies proteoform-selective caspase-2 inhibitors

The paper identifies proteoform-selective caspase-2 inhibitors using chemoproteomics, revealing a unique non-catalytic cysteine and validating their selectivity and activity.

Multi-omic stratification of the missense variant cysteinome

This paper uses chemoproteogenomics to identify gain-of-cysteine variants in cancer and healthy genomes, revealing their prevalence and potential for drug targeting.