Short-term high fat diet feeding of mice suppresses catecholamine-stimulated Ca2+ signalling in hepatocytes and intact liver.
R. P. Brumer, J. C. Correa-Velloso, S. J. Thomas, O. A. Sandiford, A. P. Thomas, P. J. Bartlett
This study shows that short-term high fat diet feeding in mice reduces norepinephrine-induced Ca2+ signaling in hepatocytes and intact liver, suggesting impaired PLC activity contributes to early NAFLD pathogenesis.
bioRxiv · Aug 28, 2022Physiology