Author

A. Panchenko

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:statistical model· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

S. Li· 2 shared D. Landsman· 1 shared D. Ostroverkhova· 1 shared T. Tie· 1 shared Y. Peng· 1 shared Y. Sheng· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 5 mutual co-author links

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2 shared papersBiophysics

S. Li

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3 papers

Recent·Most cited

Are the Next-Generation Pathogenicity Predictors Applicable to Cancer?

D. Ostroverkhova, Y. Sheng, A. Panchenko

This study evaluates next-generation pathogenicity predictors for cancer driver mutation detection, finding they perform well but lack specificity for cancer types.

bioRxiv · May 6, 2024Cancer Biology

Histone variant H2A.Z modulates nucleosome dynamics to promote DNA accessibility

S. Li, T. Tie, A. Panchenko

This study shows that H2A.Z reduces the energy barrier for DNA unwrapping, increasing DNA accessibility and nucleosome mobility.

bioRxiv · Aug 29, 2022Biophysics

DNA methylation cues in nucleosome geometry, stability, and unwrapping

S. Li, Y. Peng, D. Landsman, A. Panchenko

The paper uses molecular dynamics simulations to show that DNA methylation at CpG sites alters nucleosome geometry, stability, and unwrapping behavior.

bioRxiv · Jul 16, 2021Biophysics