Author

A. Risch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

F. Aberger· 2 shared S. Grund-Groeschke· 2 shared A. Strobl· 1 shared A. Szenes-Nagy· 1 shared C. G. Huber· 1 shared C. Sternberg· 1 shared D. Licha· 1 shared D. Neureiter· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

F. Aberger

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Oncogenic GLI1 and STAT1/3 activation drives immunosuppressive tryptophan/kynurenine metabolism via synergistic induction of IDO1 in skin cancer cells

D. P. Elmer, V. Strobl, G. Stockmaier, H.-H. Dang, M. Wiederstein, D. Licha, A. Strobl, C. Sternberg, S. Tesanovic, S. Grund-Groeschke, W. Gruber, F. Wolff, R. Moriggl, A. Risch, R. Reischl, , F. Aberger

This study identifies IDO1-kynurenine pathway activation as a novel mechanism by which HH-IL6 and GLI-STAT signaling promote immunosuppression in skin cancer, suggesting combination therapy targeting these pathways.

bioRxiv · May 4, 2020 · PreprintCancer Biology

Epidermal activation of Hedgehog signaling establishes an immunosuppressive microenvironment in basal cell carcinoma by modulating skin immunity

S. Grund-Groeschke, D. Ortner, A. Szenes-Nagy, N. Zaborsky, R. Weiss, D. Neureiter, M. Wipplinger, A. Risch, P. Hammerl, R. Greil, M. Sibilia, I. K. Gratz, P. Stoitzner, F. Aberger

This study investigates how Hedgehog signaling in skin cancer modulates immune cells and resistance to immunotherapy, identifying potential targets for combination treatments.

bioRxiv · Sep 15, 2019Cancer Biology