Cdc42 activity is essential for the interplay between cAMP/PKA pathway and CatSper function
G. M. Luque, X. Xu, A. Romarowski, M. G. Gervasi, G. Orta, J. De la Vega-Beltran, C. Stival, N. Gilio, T. Dalotto-Moreno, D. Krapf, P. E. Visconti, D. Krapf, A. Darszon, M. G. Buffone
The paper shows that Cdc42 activity is crucial for the interaction between the cAMP/PKA pathway and CatSper function in sperm, affecting Ca2+ transport and fertilization.
bioRxiv · Aug 24, 2020 · PreprintCell Biology