Author

A. Ruffin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Causey· 1 shared A. E. Mitchell· 1 shared A. J. Joglekar· 1 shared A. Morris· 1 shared A. R. Cillo· 1 shared A. Ray· 1 shared A. Somasundaram· 1 shared B. J. McVerry· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMicrobiology

A. Causey

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Novel functions of Kaposi's sarcoma herpesvirus viral FLICE inhibitory protein

K. Herold, A. Ruffin, R. Moorad, M. Constantine, A. Causey, A. E. Mitchell, J. C. Chmura, E. S. Ehrlich

This study identifies a novel function of KSHV vFLIP in enhancing NF-κB signaling by inhibiting A20's DUB activity through a SUMO interaction motif.

bioRxiv · May 31, 2022 · PreprintMicrobiology

Bifurcated monocyte states are predictive of mortality in severe COVID-19

A. R. Cillo, A. Somasundaram, F. Shan, C. Cardello, C. J. Workman, G. D. Kitsios, A. Ruffin, S. Kunning, C. Lampenfeld, S. Onkar, S. Grebinowski, G. Deshmukh, B. Methe, C. Liu, S. Nambulli, , D. A. Vignali

The paper identifies bifurcated monocyte states in severe COVID-19 patients that predict mortality, with distinct cytokine and interferon gene modules associated with survival or death.

bioRxiv · Feb 10, 2021 · PreprintImmunology