A. Morris

Population density drives increased parasitism via greater exposure and reduced resource availability in wild hosts

This study shows that higher host population density increases parasite counts through both greater exposure and reduced resource availability in red deer.

PITPβ promotes COPI vesicle fission through lipid transfer and membrane contact formation

The paper identifies PITPβ's role in COPI vesicle fission by delivering phosphatidylcholine through membrane contacts, revealing a mechanism for lipid transfer in intracellular transport.

FLASH Irradiation Regulates IFN-β induction by mtDNA via Cytochrome c Leakage

This study shows FLASH irradiation increases cytochrome c leakage from mitochondria in normal cells, reducing mtDNA accumulation and IFN-β secretion, while having the opposite effect in cancer cells.

The incidence of movement disorders increases with age and contrasts with subtle and limited neuroimaging abnormalities in argininosuccinic aciduria.

This study investigates movement disorders in argininosuccinic aciduria (ASA), finding they increase with age and show specific neuroimaging abnormalities not seen in mouse models.

The Lion's Share: Implications of carnivore diet on endangered herbivores in Tsavo

The paper analyzes lion diet in Tsavo, Kenya, finding that lions disproportionately consume endangered hirola and Grevys zebra despite their low population sizes.

Different helminth parasites show contrasting relationships with age in a wild ungulate

The paper examines age-related changes in helminth parasite infections in wild red deer, finding contrasting trends between strongyle nematodes and liver fluke/tissue worm infections.

Helminth parasites decrease survival probability in young red deer

This study shows helminth infections reduce survival in young red deer, with strongyles and Fasciola hepatica linked to lower survival in calves and yearlings.

Antibodies targeting conserved non-canonical antigens and endemic coronaviruses associate with favorable outcomes in severe COVID-19

The paper identifies antibody responses against non-canonical and endemic coronavirus antigens as predictors of favorable outcomes in severe COVID-19.

Low diversity and instability of the sinus microbiota over time in adults with cystic fibrosis

This study examines the microbiota of adults with cystic fibrosis (CF) and finds low diversity and instability in sinus microbial communities, linked to inflammation and worse sinus disease.

Ageing red deer alter their spatial behaviour and become less social

This study shows that older red deer become less socially connected and alter their spatial behavior, indicating age-related changes in social and spatial dynamics in a wild population.

Arthritis Flares Mediated by Tissue Resident Memory T Cells in the Joint

This study identifies synovial tissue-resident memory T cells as mediators of arthritis flares in murine models and finds a comparable population in human rheumatoid arthritis tissues.

CD4+ T cell lymphopenia and dysfunction in severe COVID-19 disease is autocrine TNF-α/TNFRI-dependent

The paper shows that autocrine TNF-α/TNFRI signaling drives CD4+ T cell lymphopenia and dysfunction in severe COVID-19, and TNF-α blockade improves outcomes.

Bifurcated monocyte states are predictive of mortality in severe COVID-19

The paper identifies bifurcated monocyte states in severe COVID-19 patients that predict mortality, with distinct cytokine and interferon gene modules associated with survival or death.

Evolution and adaptation of Pseudomonas aeruginosa in the paranasal sinuses of people with cystic fibrosis

This study identifies three evolutionary genetic routes of Pseudomonas aeruginosa adaptation in the sinuses of people with cystic fibrosis, suggesting sinuses may be an early site of pathoadaptation before lung infections.

Calcium ion chelation preserves platelet function during cold storage

This study identifies integrin activation and apoptosis as the mechanism of rapid platelet clearance after cold storage and shows that EGTA treatment enables cold storage of platelets for transfusion.

Multiple spatial behaviours govern social network positions in a wild ungulate

The paper uses a 43-year dataset of red deer to show how spatial behaviors and other factors shape social network positions.

Belowground changes to community structure alter methane-cycling dynamics in Amazonia

The paper measures methane flux and microbial communities across land use changes in Amazonia, finding that pasture soils emit methane while forests act as sinks, with microbial shifts driving these changes.

Fitness costs of parasites explain multiple life history tradeoffs in a wild mammal

The paper examines how parasite burdens mediate reproductive and fitness tradeoffs in red deer, showing increased parasite counts during lactation correlate with reduced survival and fecundity in the following year.

Rectal swabs in critically-ill patients provide discordant representations of the gut microbiome compared to stool samples: a brief methodologic report.

This study compares gut microbiome profiles from rectal swabs and stool samples in critically-ill patients, finding significant differences that depend on sample timing and collection method.

Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets

The paper shows that emperipolesis allows neutrophils to transfer membrane to platelets via megakaryocytes, contributing to platelet production and membrane content.

Reproduction has different costs for immunity and parasitism in a wild mammal

This study examines the relationship between reproduction, immunity, and parasitism in wild female red deer, finding that gestation reduces IgA but not parasitism, while lactation increases parasitism despite no immune cost.