Author

A. S. Avaro

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Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. Ramachandran· 1 shared C. Blanluet· 1 shared D. A. Huyke· 1 shared J. G. Santiago· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBioengineering

A. Ramachandran

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1 paper

Recent·Most cited

BioengineeringbioRxivApr 22, 2022

Detection and discrimination of single nucleotide polymorphisms by quantification of CRISPR-Cas catalytic efficiency

C. Blanluet, D. A. Huyke, A. Ramachandran…·J. G. Santiago

This paper quantifies CRISPR-Cas12 catalytic efficiency to detect and discriminate SNPs, finding that kinetic parameters like KM and [Formula] offer better discrimination than endpoint fluorescence.

DOI 10.1021/acs.analchem.2c03338

CRISPR screenstatistical model

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