A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
M. M. Drozdz, A. S. Doane, R. Alkallas, G. Desman, R. Bareja, M. Reilly, J. Bang, M. Yusupova, J. You, J. Z. Wang, A. Verma, K. Aguirre, E. Kane, I. R. Watson, O. Elemento, , J. H. Zippin
The paper identifies a nuclear cAMP microdomain that suppresses tumor growth by inhibiting YAP in the Hippo pathway.
bioRxiv · Nov 15, 2021Cancer Biology