Evolutionary Adaptations of IRG1 Refines Itaconate Synthesis and Mitigates Innate Immunometabolism Trade-offs
R. Szeligowski, F. Miros, A. Saez, M. DeCiucis, G. Wagner, H. Shen
This study investigates the evolutionary adaptations of IRG1 to refine itaconate synthesis and mitigate trade-offs in innate immunometabolism.
bioRxiv · Jun 17, 2022 · PreprintEvolutionary Biology