Author

A. Scacchetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

B. A. Garcia· 2 shared R. Bonasio· 2 shared D. Kamp· 1 shared F. Muler-Planitz· 1 shared H. J. Kim· 1 shared J. Bartho· 1 shared J. Stigler· 1 shared K. A. Janssen· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

B. A. Garcia

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Author profile →

3 papers

Recent·Most cited

ISWI catalyzes nucleosome sliding in condensed nucleosome arrays

P. Vizjak, D. Kamp, N. Hepp, A. Scacchetti, M. Gonzalez Pisfil, J. Bartho, M. Halic, P. B. Becker, M. M. Smolle, J. Stigler, F. Muler-Planitz

This study shows ISWI catalyzes nucleosome sliding in condensed chromatin and requires ATP hydrolysis for mobility, with simulations supporting a monkey-bar mechanism.

Nature Structural & Molecular Biology · Apr 25, 2024Peer-reviewedBiochemistry

Expanding the epitranscriptomic RNA sequencing and modification mapping mass spectrometry toolbox with field asymmetric waveform ion mobility and electrochemical elution liquid chromatography

R. Lauman, H. J. Kim, L. Pino, A. Scacchetti, R. Bonasio, B. A. Garcia

This paper introduces a combined FAIMS and EMLC approach to improve RNA modification detection and sequencing in complex samples.

bioRxiv · Oct 28, 2022Biochemistry

Permethylation of ribonucleosides provides enhanced mass spectrometry quantification of post-transcriptional modifications

Y. Xie, K. A. Janssen, A. Scacchetti, R. Bonasio, B. A. Garcia

This paper introduces a method to enhance RNA modification analysis using permethylation and LC-MS/MS, showing improved detection of cytosine methylation and hydroxymethylation in mouse embryonic stem cells.

bioRxiv · Jan 26, 2022Biochemistry