Author

M. Halic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 4 Approach:experimental assay· 4 Assay:structural biology· 2 Assay:ChIP-seq· 1 Organism:Drosophila· 1 Organism:human· 1

Frequent Co-Authors

S. Bilokapic· 2 shared A. Ali-Ahmad· 1 shared A. Sabantsev· 1 shared A. Scacchetti· 1 shared D. Dimakou· 1 shared D. Kamp· 1 shared D. Malik· 1 shared F. Muler-Planitz· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersBiophysics

S. Bilokapic

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4 papers

Recent·Most cited

ISWI catalyzes nucleosome sliding in condensed nucleosome arrays

P. Vizjak, D. Kamp, N. Hepp, A. Scacchetti, M. Gonzalez Pisfil, J. Bartho, M. Halic, P. B. Becker, M. M. Smolle, J. Stigler, F. Muler-Planitz

This study shows ISWI catalyzes nucleosome sliding in condensed chromatin and requires ATP hydrolysis for mobility, with simulations supporting a monkey-bar mechanism.

Nature Structural & Molecular Biology · Apr 25, 2024Peer-reviewedBiochemistry

Histone modifications regulate pioneer transcription factor cooperativity

K. Sinha, S. Bilokapic, Y. Du, D. Malik, M. Halic

This study shows how histone modifications influence the cooperative binding of pioneer transcription factors Oct4 and Sox2, affecting chromatin structure and pluripotency.

bioRxiv · Mar 14, 2023 · PreprintBiophysics

Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

L. Bacic, G. Gaullier, A. Sabantsev, L. Lehmann, K. Brackmann, D. Dimakou, M. Halic, G. Hewitt, S. J. Boulton, S. Deindl

This study determines the structure of ALC1 bound to a PARylated nucleosome using cryo-EM, revealing intermediate states and functional roles in nucleosome remodeling.

bioRxiv · Jun 18, 2021Biophysics

CENP-C unwraps the CENP-A nucleosome through the H2A C-terminal tail

A. Ali-Ahmad, S. Bilokapic, I. B. Schafer, M. Halic, N. Sekulic

This paper investigates how CENP-C interacts with CENP-A nucleosomes, revealing structural changes that distinguish centromeric from canonical nucleosomes.

bioRxiv · Jul 31, 2019 · PreprintBiochemistry