ISWI catalyzes nucleosome sliding in condensed nucleosome arrays
P. Vizjak, D. Kamp, N. Hepp, A. Scacchetti, M. Gonzalez Pisfil, J. Bartho, M. Halic, P. B. Becker, M. M. Smolle, J. Stigler, F. Muler-Planitz
This study shows ISWI catalyzes nucleosome sliding in condensed chromatin and requires ATP hydrolysis for mobility, with simulations supporting a monkey-bar mechanism.
Nature Structural & Molecular Biology · Apr 25, 2024Peer-reviewedBiochemistry