Author

A. Shemorry

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cancer Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

C. J. Essenburg· 1 shared C. R. Graveel· 1 shared D. Maddalo· 1 shared E. A. Tovar· 1 shared E. Levy· 1 shared E. Villemure· 1 shared E. Wolfrum· 1 shared F. Peale· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

C. J. Essenburg

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1 paper

Recent·Most cited

Engineering ERα degraders with pleiotropic ubiquitin ligase ligands maximizes therapeutic efficacy by co-opting distinct effector ligases

A. Shemorry, W. den Besten, M. M. Mulvihill, C. J. Essenburg, N. Blaquiere, T. Kleinheinz, E. Villemure, F. Peale, G. Deshmukh, D. Maddalo, E. Levy, K. Yu, E. A. Tovar, E. Wolfrum, R. A. Blake, , I. E. Wertz

This study evaluates bifunctional ER degraders with different ubiquitin ligase ligands, finding that pan-IAP antagonists enhance ER degradation and induce TNF-dependent cell death more effectively than existing therapies.

bioRxiv · Jun 9, 2024Cancer Biology