Chemically Accurate Relative Folding Stability of RNA Hairpins from Molecular Simulations
L. G. Smith, Z. Tan, A. Spasic, D. Dutta, L. A. Salas-Estrada, A. Grossfield, D. Mathews
This study compares simulated and experimental free energies of RNA hairpins to assess force field accuracy and proposes methods to improve simulation convergence.
bioRxiv · Jun 22, 2018Biophysics