BiophysicsbioRxiv
Chromatin-loop extrusion and chromatin unknotting
D. Racko, F. Benedetti, D. Goundaroulis, A. Stasiak
The paper shows chromatin-loop extrusion actively unknots chromatin fibres in interphase chromosomes, preventing excessive knotting despite topoisomerase activity.
DOI 10.3390/polym10101126