F. Benedetti

Tumor-reactive clonotype dynamics underlying clinical response to TIL therapy in melanoma

This study tracks tumor-reactive TIL clonotypes in melanoma patients before and after TIL-ACT to identify factors associated with clinical response.

Global gradients in species richness of marine plankton functional groups

The paper estimates global species richness of marine plankton functional groups using environmental predictors and finds latitudinal gradients vary by group with temperature and nutrients as key drivers.

Tumor Microenvironment Cellular Crosstalk Predicts Response to Adoptive TIL Therapy in Melanoma

This study identifies CD8+ TIL-myeloid cell networks as predictors of response to adoptive TIL therapy in melanoma using single-cell RNA-seq and spatial proteomic analyses.

Copepod functional traits and groups show divergent biogeographies in the global ocean

This study identifies 11 copepod functional groups with distinct biogeographic patterns, linking their traits to environmental niches and ocean regions.

Patterns of mesozooplankton community composition and vertical fluxes in the global ocean

This study analyzes global ocean zooplankton community composition and vertical particle fluxes, finding that oxygen minima reduce zooplankton abundance but weaken particle flux attenuation.

Identification and characterization of human CD34+ and CD34dim/- neutrophil committed progenitors

The paper identifies and characterizes CD34+ and CD34dim/- neutrophil-committed progenitors in human bone marrow, revealing their maturation stages and association with chronic myeloid leukemia.

Chromatin-loop extrusion and chromatin unknotting

The paper shows chromatin-loop extrusion actively unknots chromatin fibres in interphase chromosomes, preventing excessive knotting despite topoisomerase activity.