Inosine Triphosphate Pyrophosphatase as a Candidate Associated with White Matter Abnormalities in Chronic Heart Failure
K. Takeuchi, Hideaki Suzuki, A. Sumiyoshi, R. Kurosawa, A. Sugano, T. Urushihata, M. Arai, K. Nochioka, K. Ito, A. Satoh, T. Nakazawa, S. Yasuda
This study identifies inosine triphosphate pyrophosphatase (ITPA) as a candidate factor linking chronic heart failure and white matter abnormalities through human, animal, and cellular analyses.
bioRxiv · Nov 4, 2026 · PreprintNeuroscience