mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming
H. Bischof, S. Maier, P. Koprowski, B. Kulawiak, S. Burgstaller, J. Jasinska, K. Serafimov, M. Zochowska, D. Gross, W. Schroth, L. Matt, D. A. Juarez Lopez, Y. Zhang, I. Bonzheim, F. A. Büttner, , R. Lukowski
This study identifies mitoBKCa, a BKCa splice variant in mitochondria of breast cancer cells, showing it modulates energy production and promotes proliferation, suggesting it as a potential therapeutic target.
bioRxiv · Oct 2, 2023 · PreprintCancer Biology