An early Myc-dependent transcriptional program underlies enhanced macromolecular biosynthesis and cell growth during B-cell activation
A. Tesi, S. De Pretis, M. Furlan, M. Filipuzzi, M. J. Morelli, A. Andronache, M. Doni, A. Verrecchia, M. Pelizzola, B. Amati, A. Sabo
This study identifies a Myc-dependent transcriptional program in activated B-cells that drives macromolecular biosynthesis and cell growth, also found in B-cell lymphomas.
bioRxiv · Mar 4, 2019Cancer Biology