Author

M. Filipuzzi

Primary ORCID profile (0000-0002-4584-4114 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

M. FilipuzziiD1 paper · European Institute of Oncology

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 4 Approach:experimental assay· 4 Research Focus:cancer & tumor microenvironment· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

B. Amati· 4 shared M. Doni· 4 shared A. Sabo· 3 shared A. Verrecchia· 3 shared A. Bisso· 2 shared D. Olivero· 2 shared D. Pasini· 2 shared G. Ceccotti· 2 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersCancer Biology

B. Amati

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4 papers

Recent·Most cited

Polycomb Group Ring Finger Protein 6 suppresses Myc-induced lymphomagenesis

N. Tanaskovic, M. Dalsass, G. Ceccotti, M. Filipuzzi, A. Verrecchia, P. Nicoli, M. Doni, D. Olivero, D. Pasini, H. Koseki, A. Sabo, A. Bisso, B. Amati

This study shows that Pcgf6 loss accelerates Myc-induced lymphomagenesis in mice, despite no impact on transcriptional profiles.

bioRxiv · Dec 2, 2021Cancer Biology

Targeting mitochondrial respiration and the BCL2 family in MYC-associated B-cell lymphoma

G. Donati, M. Rava, M. Filipuzzi, P. Nicoli, L. Cassina, A. Verrecchia, M. Doni, S. Rodighiero, F. Parodi, A. Boletta, C. P. Vellano, J. R. Marszalek, G. Draetta, B. Amati

This paper identifies OxPhos as a key MYC-driven process in DLBCL and shows that targeting ETC complex I with IACS-010759 synergizes with BCL2 inhibitors to kill lymphoma cells.

bioRxiv · Nov 22, 2020Cancer Biology

Cooperation between MYC and β-catenin in liver tumorigenesis requires Yap/Taz

A. Bisso, M. Filipuzzi, G. P. Gamarra Figueroa, G. Brumana, F. Biagioni, M. Doni, G. Ceccotti, N. Tanaskovic, M. J. Morelli, V. Pendino, F. Chiacchiera, D. Pasini, D. Olivero, S. Campaner, A. Sabo, B. Amati

This study shows that Yap/Taz mediate the cooperation between MYC and β-catenin in liver tumorigenesis, identifying a prognostically significant gene signature in human hepatocellular carcinomas.

bioRxiv · Oct 25, 2019Cancer Biology

An early Myc-dependent transcriptional program underlies enhanced macromolecular biosynthesis and cell growth during B-cell activation

A. Tesi, S. De Pretis, M. Furlan, M. Filipuzzi, M. J. Morelli, A. Andronache, M. Doni, A. Verrecchia, M. Pelizzola, B. Amati, A. Sabo

This study identifies a Myc-dependent transcriptional program in activated B-cells that drives macromolecular biosynthesis and cell growth, also found in B-cell lymphomas.

bioRxiv · Mar 4, 2019Cancer Biology