Author

A. Tobi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

T. Teesalu· 3 shared A. D. Davidson· 1 shared A. Helenius· 1 shared A. Rinken· 1 shared B. M. Collins· 1 shared B. Mollenhauer· 1 shared B. Simonetti· 1 shared C. Anton-Plagaro· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersCell Biology

T. Teesalu

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ESCPE-1 Mediates Retrograde Endosomal Sorting of the SARS-CoV-2 Host Factor Neuropilin-1

B. Simonetti, J. L. Daly, L. Simon-Gracia, K. Klein, S. Weeratunga, C. Anton-Plagaro, A. Tobi, L. Hodgson, P. Lewis, K. J. Heesom, D. K. Shoemark, A. D. Davidson, B. M. Collins, T. Teesalu, Y. Yamauchi, P. J. Cullen

The paper identifies Neuropilin-1 as a retrograde cargo of ESCPE-1 and shows ESCPE-1 mediates its trafficking, potentially facilitating SARS-CoV-2 infection.

bioRxiv · Jan 20, 2022Cell Biology

PL1 Peptide Engages Acidic Surfaces on Tumor-Associated Fibronectin and Tenascin Isoforms to Trigger Cellular Uptake.

P. Lingasamy, K. Posnograjeva, S. Kopantsuk, A. Tobi, A. Rinken, I. J. General, E. Asciutto, T. Teesalu

PL1 peptide binds acidic surfaces on tumor-associated Fibronectin EDB and Tenascin C-C to enable cellular uptake of functionalized nanoparticles.

bioRxiv · Sep 16, 2021Cancer Biology

Neuropilin-1 facilitates SARS-CoV-2 cell entry and provides a possible pathway into the central nervous system

L. Cantuti-Castelvetri, R. Ohja, L. Pedro, M. Djannatian, J. Franz, S. Kuivanen, K. Kallio, T. Kaya, M. Anastasina, T. Smura, L. Levanov, L. Szirovicza, A. Tobi, H. Kallio-Kokko, P. Osterlund, , M. Simons

This study shows that neuropilin-1 enhances SARS-CoV-2 infectivity and facilitates viral entry into the central nervous system via the olfactory pathway.

Science · Nov 13, 2020Peer-reviewedMicrobiology